Dr.Gayathri Devi D

 Gayathri

Dr.Gayathri Devi D

Assistant Professor in Biochemistry,
Department of Life Sciences
University of Calicut, Thenhipalam
Kerala – 673 635
Phone:  +919447712539
Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.

ResearcherID1 orcidid scholar scopusicon Researchgate

Qualifications

  • Ph.D. in Biochemistry (December 2010), University of Kerala
  • M. Phil. in Biochemistry (June 2003), University of Kerala
  • M.Sc. Biochemistry (2001), University of Kerala

Publications

  1. N George, D Gayathri Devi. Regulating Enzyme Catalysis by Tailored Silver Nanocrystals Fabricated with Holigarna arnottiana—Synthesis, Characterization, and Performance Optimization.Biological Trace Element Research 202 (9), 4240-4259 (2024)
  2. K Merin Rinky, D Gayathri Devi, VK Priya. Fagopyrin F fraction from Fagopyrum tataricum demonstrates photodynamic inactivation of skin infecting bacterium and squamous cell carcinoma (A431) cells. Photochemical & Photobiological Sciences, 1-19 (2024)
  3. N George, D Gayathri Devi.Phytonano silver for cosmetic formulation- synthesis, characterization, and assessment of antimicrobial and antityrosinase potential. Discover Nano
  4. K. P. Lijith. K. Merin Rinky. D. Gayathri Devi. Purification, characterization and antioxidant efficacy testing of trypsin inhibitor protein from Anonna squamosa seeds. Journal of Plant Biochemistry and Biotechnology. https://doi.org/10.1007/s13562-022-00789-y
  5. Chanchitha Chandran, P. Smitha & D. Gayathri Devi. Seed Protein from Artocarpus hirsutus Lam. with Trypsin Inhibitory, Microbicidal and Antioxidant Activities Induces Depletion of Human Skin Cancer (A431) and Colon Cancer (HT29) Cells. Journal of Biologically Active Products from Nature. DOI: 10.1080/22311866.2021.2008269 (2022)
  6. Merin Rinky K, Lijith K P, Chanchitha Chandran and Gayathri Devi D. Identification of Artocarpus hirsutus and Garcinia gummi-gutta as the sources of trypsin inhibitory proteins whose activity can be modulated by industrial additives. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] (2021).
  7. Merin Rinky K., Jiji R and Gayathri Devi. D. Garcinia cambogia L. seeds as a source of oil and a trypsin inhibitory protein having microbicidal and antioxidant potentials. Science, Technology and Development 9 (2), 76-81 (2020).
  8. Sajil K.K. and Gayathri Devi. D. Study on Antioxidant Activity of Ipomoea sepiaria Koenig Ex. Roxb. and Evolvulus alsinoide Linn. by DPPH, FRAP and ABTS Methods. Science, Technology and Development 9 (2), 103-107 (2020).
  9. M.S. Soumya, D. Gayathri Devi, K.M. Shafeekh, Suresh Das and Annie Abraham. Photodynamic therapeutic efficacy of symmetrical diiodinated squaraine in in vivo skin cancer models. Photodiagnosis and Photodynamic Therapy 18, 302–309 (2017).
  10. T.R.Cibin, Gayathri Devi. D., D. Ramaiah and Annie Abraham
    "Squaraine PDT induces oxidative stress in skin tumor of swiss albino mice", Proc. SPIE 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II, 75761P (February 16, 2010); doi:10.1117/12.842288; http://dx.doi.org/10.1117/12.842288
  11. Annie Abraham, Gayathri Devi. D., T.R. Cibin and D. Ramaiah
    "Two different approaches in skin cancer therapy: using a photosensitizer/a natural product", Proc. SPIE 7576, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications II, 757603 (February 16, 2010); doi:10.1117/12.842245; http://dx.doi.org/10.1117/12.842245
  12. Gayathri Devi. D, Cibin T. R. and Annie Abraham. Bis (3, 5-diiodo-2, 4, 6-trihydroxyphenyl) squaraine photodynamic therapy induces in vivo tumor ablation by triggering cytochrome c dependent mitochondria mediated apoptosis. Photodiagnosis and Photodynamic Therapy 10, 510-517 (2013).
  13. Cibin T. R., Gayathri Devi. D and Annie Abraham. Chemoprevention of Two- Stage Skin Cancer In vivo by Saraca asoca. Integrative Cancer Therapies. 11(3), 279- 286 (2012).
  14. Cibin TR, Gayathri Devi D and Annie Abraham. Chemoprevention of Skin Cancer by the Flavonoid Fraction of Saraca asoka. Phytotherapy Research. DOI: 10.1002/ptr.2950. (2009).
  15. Gayathri Devi. D, Cibin T. R, Ramaiah. D and Annie Abraham. Bis (3, 5-diiodo-2, 4, 6-trihydroxyphenyl) squaraine: a novel candidate in Photodynamic Therapy for skin cancer models in vivo. Journal of Photochemistry and Photobiology B: Biology 92,153–159(2008).
  16. Cibin T. R, Srinivas. G, Gayathri Devi. D, Priya Srinivas, Lija. Y and Annie Abraham. Antioxidant and Antiproliferative Effects of Flavonoids from Emilia sonchifolia Linn on Human Cancer Cells. Int. J. Pharmacol. 2(5), pp520-524 (2006).
  17. Gayathri Devi V, Biju P.G, Gayathri Devi D, Cibin T.R, Lija Y and Annie Abraham. Isolation of Robinetin from Adenanthera pavonina and its protective effects on perchlorate induced oxidative damage. J. Trop. Med. Plants., 7 (1), pp111-117 (2006).
  18. Gayathri Devi. D, Lija. Y, Cibin T. R, Biju. P.G, Gayathri Devi. V and Annie Abraham. Evaluation of the protective effects of Emilia sonchifolia Linn. (DC.) on perchlorate-induced oxidative damage. J. Biol. Sci. 6(5), pp887-892(2006).

Conference Publications

  1. Gayathri Devi. D and Annie Abraham; Protective effect of Emilia sonchifolia. Linn. on perchlorate induced toxicity in experimental animal models: National symposium on Toxicology and Good Laboratory Practice, held at Sree Chitra Tirunal Institute, Trivandrum, Oct 2004.
  2. Gayathri Devi. D, Gayathri Devi. V and Annie Abraham; In vitro evaluation of the antioxidative effect of Emilia sonchifolia. Linn.: 17th Kerala Science Congress, held at KFRI, Peechi, Jan 2005.
  3. Gayathri Devi. V, Gayathri Devi. D and Annie Abraham; Antioxidant properties of Adenanthera pavonina Linn.Proc.on: Natural products, free radicals and radio protectors in health, Annamalai University, Tamil Nadu, 2004
  4. Gayathri Devi. D, Cibin T. R, Ramaiah. D and Annie Abraham. Bis (3, 5-diiodo-2, 4, 6-trihydroxyphenyl) squaraine: a novel candidate in Photodynamic Therapy in vivo. International Symposium on Genomic Instability and Cancer, University of Kashmir & Ohio State University, USA, July 2007. (Best poster Award)
  5. Cibin T. R, Gayathri Devi. D and Annie Abraham. Efficacy of Saraka asoka in the modulation of DMBA induced skin carcinogenesis in swiss albino mice. International Symposium on Genomic Instability and Cancer, University of Kashmir & Ohio State University, USA, July 2007.
  6. Cibin. T R, Gayathri Devi. D, and Annie Abraham. Two Different Approaches in Cancer Therapy-using Photosensitizer and Natural Product, 20th Kerala Science Congress, held at Thiruvananthapuram, Jan 2008.
  7. Gayathri Devi. D, Cibin T. R, Ramaiah. D and Annie Abraham. Bis (3, 5-diiodo-2, 4, 6-trihydroxyphenyl) squaraine: A Novel Candidate in Photodynamic Therapy in vivo., National Workshop on Genomics and Proteomics, Kerala University, March 2008.
  8. Gayathri Devi. D, Cibin T. R and Annie Abraham. Tumor site- targeted Induction of Oxidative damage by Bis (3, 5-diiodo-2, 4, 6-trihydroxyphenyl) squaraine mediated Photodynamic Therapy, Indian Science Congress, Thiruvananthapuram, January 2010.
  9. Chanchitha Chandran and Gayathri Devi. D. Screening and Isolation of Trypsin Inhibitors from Some Indigenous Plants of Kerala, World Congress on Drug Discovery and Development, Bangalore, November 2016.
  10. Chanchitha Chandran and Gayathri Devi. D. Chromatographic purification of Trypsin Inhibitors (TIs) from Atrocarpus hirsutus and Garcinia cambogia, International Conference on Nutraceuticals and Chronic Diseases, Goa, September 2017.
  11. Merin Rinky K and Gayathri Devi. D. Effects of Different Additives on Partially Purified Trypsin Inhibitor from  Atrocarpus hirsutus Seeds, 30th Kerala Science Congress, Thalassery, January 2018.
  12. Merin Rinky K, Smitha. P and Gayathri Devi. D. Isolation, partial purification and Characterization of Trypsin Inhibitor from Atrocarpus hirsutus Seeds and its Effect on selected microbes.  International Seminar on Recent Biochemical Approaches in Therapeutics. Thiruvananthapuram, 23rd-25th January 2018.
  13. Lijith K.P. and Gayathri Devi. D. Garcinia cambogia Trypsin Inhibitor: Partial Putification and Modulation of its Activity by Different Additives. International Seminar on Recent Biochemical Approaches in Therapeutics. Thiruvananthapuram, 23rd-25th January 2018.

Research Projects Undertaken

Title : Screening of five indegenous plants of Kerala for     trypsin    inhibitors – their isolation, characterisation and effects on cancer cells

Duration                                  : 3 years (2014-2017)

Funding Agency                     : DST-SERB

Amount Sanctioned                : Rs. 18,30,000/-

Research guidance

Completed :

M.Phil (1)

M.Sc. Dissertations (8)

Ongoing:

Ph.D (4)

Teaching experience

6 Years (PG level)

Assistant Professor - Department of Life Sciences, University of Calicut (28th March 2012 onwards)

Membership in Academic bodies

  1. Member, Board of studies in Biochemistry (combined) University of Calicut (2013-2017, 2017-Present)
  2. Chairman board of examiners in M.Sc. Biochemistry (CSS) of University of Calicut (2016 onwards)
  3. Member, Board of studies in Medical Biochemistry (combined) Kannur University (2018 onwards)
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