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Life Sciences

Life Sciences

Life Sciences

Life Sciences

Life Sciences

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Life Sciences

The Department of Life Sciences at the University of Calicut was established in February 1978, towards the end of the fifth plan period, with support from the University Grants Commission (UGC). It originated from a proposal to promote integrated teaching and research in Physiology, Biochemistry, and Microbiology, an interdisciplinary approach strongly recommended by a UGC review committee that has since proven highly effective.

 

News & Updates

Latest Publications
  1. Sneha Das, Kainoor Krishnankutty Janardhanan, & B.S. Harikumaran Thampi. Bioactive Extract of Morel Mushroom, Morchella esculenta (Ascomycota) Attenuates Doxorubicin-Induced Oxidative Stress Leading to Myocardial Injury. International Journal of Medicinal Mushrooms, 24(8):31 – 44 (2022) https://doi.org/10.1615/IntJMedMushrooms.2022044516
  2. K. P. Lijith. K. Merin Rinky. D. Gayathri Devi. Purification, characterization and antioxidant efficacy testing of trypsin inhibitor protein from Anonna squamosa seeds. Journal of Plant Biochemistry and Biotechnology. https://doi.org/10.1007/s13562-022-00789-y
  3. Chanchitha Chandran, P. Smitha & D. Gayathri Devi. Seed Protein from Artocarpus hirsutus Lam. with Trypsin Inhibitory, Microbicidal and Antioxidant Activities Induces Depletion of Human Skin Cancer (A431) and Colon Cancer (HT29) Cells. Journal of Biologically Active Products from Nature. (2022) https://doi.org/10.1080/22311866.2021.2008269
  4. Preenanka R, Denoj Sebastian. Characterization of green synthesized antibacterial silver nanoparticles from Amaranthus spinosus L. Extract. Bionanoscience. (2022) (Impact Factor: 2.305). https://doi.org/10.1007/s12668-022-00965-3
  5. Abhini KN, Akhila B Rajan, Fathimathu Zuhara K and Denoj Sebastian. Response surface methodological optimization of L-asparaginase production from a medicinal plant endophyte Acinetobacter baumannii ZAS1. J Genet Eng Biotechnol 20, 22 (2022). (Impact Factor: 3.818, Scopus CiteScore 5.5) https://doi.org/10.1186/s43141-022-00309-4
  6. Rinju R and B S Harikumaran Thampi Characteristics of Starch Extracted from the Stem of Pineapple Plant (Ananas comosus) - an Agro Waste from Pineapple Farms Brazilian Archives of Biology and Technology 2021 https://doi.org/10.1590/1678-4324-2021190276
  7. Merin Rinky K, Lijith K P, Chanchitha Chandran and Gayathri Devi D. Identification of Artocarpus hirsutus and Garcinia gummi-gutta as the sources of trypsin inhibitory proteins whose activity can be modulated by industrial additives. Indian Journal of Natural Products and Resources (IJNPR) 2021
  8. J Puthukkara, S. Renganathan, A Menon, RG Pillai, Beneficial impacts of Astaxanthine on biomarkers of antioxidant status and oxidative damage in rats exposed to ambient air,  Chem boil Letters 2021  http://thesciencein.org/cbl
  9. Liji. P, Sinosh Skariyachan and B. S. Harikumaran Thampi. Cytotoxic effects of butyric acid derivatives through GPR109A receptor in Colorectal Carcinoma cells by in silico and in vitro methods Journal of Molecular Structure 2021  https://doi.org/10.1016/j.molstruc.2021.130832
  10. N. S. Rajendran and B.S. Harikumaran Thampi. Extraction, rheological and textural analyses and grading of pectin from stem pith of banana… Ukrainian Food Journal  2021 10.24263-2304-974X-2021-10-1-11
  11. N. S. Rajendran and B.S. Harikumaran Thampi. Pectin—Extraction from underground stem of banana and its structural, rheological, and textural analyses and grading Journal of Food processing and technology 2021 https://doi.org/10.1111/jfpp.15332
  12. Smitha Renganathan, Radhakrishna Gopala Pillai Preliminary analysis of phytochemicals and in vitro free radical scavenging activity of Dhanwantaram Kashayam Adv Biotechnol Exp Ther 2021 https://doi.org/10.5455/jabet.2021.d110
  13. Rasiya K.T, Denoj Sebastian Iturin and surfactin from the endophyte Bacillus amyloliquefaciens strain RKEA3 exhibits antagonism against Staphylococcus aureus Biocatalysis and Agricultural Biotechnology 2021 https://doi.org/10.1016/j.bcab.2021.102125
  14. Ambili M, Denoj Sebastian Evaluation of Sensitivity and Cost-Effectiveness of Molecular Methods for the Co-detection of Waterborne Pathogens in India Evaluation of sensitivity and cost effectiveness of molecular methods for the co-detection of waterborne pathogens in India 2021 https://doi.org/10.1007/s10126-021-10078-9
  15. Sajil K.K. and Gayathri Devi. D. Study on Antioxidant Activity of Ipomoea sepiaria Koenig Ex. Roxb. and Evolvulus alsinoide Linn. by DPPH, FRAP and ABTS Methods. Science, Technology and Development 2020
  16. S Renganathan, RG Pillai, Anti oxidant activities of Dhanwantaram Kashayam –an Ayurvedic polyherbal formulation alleviates diabetic complications in rats, J Diab and Metab disorders. 2020 10.1007/s40200-020-00655-5
  17. "RGPillai Antiproliferative actions of Ziziphus jujube fruit extract is mediated through alterations in Bcl2-Bax ration and through the activation of caspases. Chem Biol Let, 2020 "
  18. Sreena C.P., Denoj Sebastian Arecanut husk: A potential feedstock for enhanced production of endoglucanase by Bacillus subtilis MU S1. Environmental Technology & Innovation. 2020  https://doi.org/10.1016/j.eti.2020.100989
  19. S Renganathan, AS Srivastava, RG Pillai Dhanwantharam kashayam, an Ayurvedic Polyherbal Formulation, Reduces Oxidative Radicals and Reverts Lipids Profile towards Normal in Diabetic Rats Biochemistry and biophysics reports 2020 https://doi.org/10.1016/j.bbrep.2020.100755
  20. Merin Rinky K., Jiji R and Gayathri Devi. D. Garcinia cambogia L. seeds as a source of oil and a trypsin inhibitory protein having microbicidal and antioxidant potentials. Science, Technology and Development 2020
  21. Chithra Pillai, K.V. Faseela and Harikumaran Thampi. Nutritional composition of selected traditional rice varieties of Kerala Journal of Tropical Agriculture 2020
  22. Liji. P and B. S. Harikumaran Thampi. Invitro evaluation of apoptotic induction of butyric acid derivatives in colorectal carcinoma cells. Anticancer research. 2019 http://10.21873/anticanres.13528
  23. Ambili M and Denoj Sebastian. Assessment of bacteriological quality of drinking water from North Kerala, India. Biosci. Biotech. Res. Comm. 12(2) 2019 http://dx.doi.org/10.21786/bbrc/12.2/5
  24. Rinju R and B S Harikumaran Thampi Characterization studies on starch extracted from the. stem of pineapple plant (Ananas comosus) at different. growth stages. Environmental Communication. Biosci. Biotech. Res. Comm. 2019 http://10.21786/bbrc/12.3/37
  25. MC Sereena, D Sebastian. Cloning, expression and characterization of the anticancer protein azurin from an indigenous strain Pseudomonas aeruginosa SSj". International Journal of Peptide Research and Therapeutics. 2019 https://doi.org/10.1007/s10989-019-09924-1
  26. Sabu V…….RG Pillai, Combinatorial Action of Triterpenoid, Flavonoid, and Alkaloid on Inflammation Natural Product Communications 2019 https://doi.org/10.1177/1934578X19868877
  27. MC Sereena, D Sebastian. Evaluation of Anticancer and Anti-hemolytic Activity of Azurin, a Novel Bacterial Protein from Pseudomonas aeruginosa Ssj. International Journal of Peptide Research and Therapeutics 2019 https://doi.org/10.1007/s10989-019-09851-1.
  28. N. S. Rajendran and B.S. Harikumaran Thampi. Extraction and characterisation of pectin from Banana peel. Carpathian  Journal of food science and technology.  2019 https://doi.org/10.34302/2019.11.4.4
  29. Sreena C.P., Denoj Sebastian. Jackfruit outer rind: A sustainable feedstock for fermentable sugar production using recombinant endoglucanase from Bacillus subtilis MU S1. Environmental Technology & Innovation. 2019 https://doi.org/10.1016/j.eti.2019.100448
  30. I C Renu and B S Harikumaran Thampi. Studies on Collagen Hydrolysis by Pineapple (Ananas Comosus) Stem Bromelain. International Journal of Pharmacy and Biological Sciences. 2019
  31. C.P.Sreena, Denoj Sebastian. Augmented cellulase production by Bacillus subtilis strain MU S1 using different statistical experimental designs. Journal of Genetic Engineering and Biotechnology 2018 https://doi.org/10.1016/j.jgeb.2017.12.005
  32. B Kavuthodi, D Sebastian Biotechnological valorization of pineapple stem for pectinase production by Bacillus subtilis BKDS1: Media formulation and statistical optimization for submerged fermentation. Biocatalysis and agricultural biotechnology. 2018 https://doi.org/10.1016/j.bcab.2018.05.003.
  33. Sereena .M.C, Denoj Sebastian. Characterization of anticancer compound azurin from indigenous isolate Pseudomonas aeruginosa Ssj. International Journal of Life Sciences Research. 2018
  34. Emmanuel Simon, Aswini Poyyakkara, Sameer Kumar and Gokuldas Mankadath. Curcumin and its synthetic analogue dimethoxycurcumin differentially modulates antioxidant status of normal human peripheral blood mononuclear cells. Free Radical Research 2018 https://doi.org/10.1080/10715762.2018.1455002
  35. P.G. Sreejesh and E. Sreekumaran. Effect of monosodium glutamate on striato-hippocampal acetylcholinesterase level in the brain of male Wistar albino rats and its implications on learning and memory during aging. , Bioscience Biotechnology Research Communications 2018 http://dx.doi.org/10.21786/bbrc/11.1/11
  36. Bijesh Kavuthodi, Denoj Sebastian. Response Surface Methodological Approach to Optimize the Critical Medium Components for Augmented Pectinase Production by Bacillus subtilis BKDS1. Journal of Pure and Applied Microbiology 2018 http://dx.doi.org/10.22207/JPAM.12.2.62
  37. Bijesh Kavuthodi and Denoj Sebastian. Review on bacterial production of alkaline pectinase with special emphasis on Bacillus species. Microbiological Communication. Biosci. Biotech. Res. Comm. 2018 http://dx.doi.org/10.21786/bbrc/11.1/4
  38. Seena T. Pandarekandy, P. G. Sreejesh, B. S. Harikumaran thampi and E. Sreekumaran. Hypoglycaemic Effect of Glibenclamide: A Critical Study on the Basis of Creatinine and Lipid Peroxidation Status of Streptozotocin-induced Diabetic Rat. Indian Journal of Pharmaceutical Sciences 2017 10.4172/pharmaceutical-sciences.1000290
  39. M.S. Soumya, Gayathri Devi. D, K.M. Shafeekh, Suresh Das and Annie Abraham. Photodynamic therapeutic efficacy of symmetrical diiodinated squaraine in in vivo skin cancer models.   Photodiagnosis and Photodynamic Therapy 2017 10.1016/j.pdpdt.2017.03.009
  40. Shaheedha, Sreena C P, Denoj Sebastian. Poultry Feeds as Carriers of Antibiotic Resistant Enterobacteriaceae. Int J Pharma Res Health Sci. 2017 http://dx.doi.org/ 10.21276/ijprhs.2017.06.10
  41. Greeshma C, Varun, Sreekumaran E. Supplementation of zinc induces retinoic acid-mediated differentiation of rat bone marrow mesenchymal stem cells (MSCS) into insulin producing cells (ipcs) in-vitro. International Journal of Research in Ayurveda and Pharmacy. 2017 10.7897/2277-4343.08150
  42. Panavalappil Greeshma, Korattuvalappil S. Ravikumar , Mangalathmelathil N. Neethu, Meera Pandey,  Karattuthodi Fathimathu Zuhara, Kainoor K. Janardhanan Antioxidant Anti-inflammatory and Antitumor activities of cultured mycelia and fruiting bodies of an edible mushroom, Hypsizygus ulmarius (Bull.:Fr.) International journal of Medicinal Mushrooms. 2016 10.1615/IntJMedMushrooms.v18.i3.60
  1. Sereena MC, Sreena CP and Denoj Sebastian. 2016. Bioprospecting Of Native Pseudomonas Isolates From Western Ghats For Anticancer Agents. In Sustainable Biotechnology. K. Mashhoor., Ruba Badharudheen and Joysi S Job. eds.. pp 68-72. ISBN: 978-3-659-89742-9
  2. Dr. G. Radhakrishna Pillai. Protocols in cell and molecular biology. 2017. University of Calicut. ISBN:978-93-5351-499-0
  3. Dr. Radhakrishna G Pillai. Cell Biology and Biochemistry A Technical Perspective, 2017, University of Calicut Centre for Development of Science and Technology. ISBN 978 93 5288 2021
  4. N. S. Rajendran and B.S. Harikumaran Thampi. A handbook in connection with International Seminar. Pectin Extraction from stem pith of banana; structural and rheological charecterization in Modern trends in biological sciences. 2019. University of Calicut, Sooryagatha Publishers, Kochi, ISBN : 97881725511216
  5. Dr. Gayathri Devi. D. Perspectives in Life Sciences. 2020. University of Calicut UGC HRDC, University of Calicut in association with SPCS Kottayam. ISBN: 978-93-88992-90-9

 

Seminar/ Workshops/ Webinars

No Name of the workshop/ seminar Date
1 One day Training programme for school biology teachers on microscopy in association of Kerala Sasthra Sahithya Parishad, Malappuram. 10-08-2016
2 Frontier lecture by Dr.Sajish Mathew “tRNA synthetase as modulators of stress signalling and Novel  transcriptors in metabolic disorders 22-08-2016
3 Prof.Dr.VKSasidharan Endowment talk by Dr.Chirsthunesa Soundararaj on  “Overcoming the selective permeability of blood brain barrier -  current strategy. 14-03-2017
4 Children’s Science Congresssponsored by the Kerala State Science Technology and Environment on the topic “World of Microbes” 20-04-2017
5 Two days national seminar “Trends in Microbiology” 26-09-2017
6 Sasthrayaan of RUSA exhibiting the facilities to the general public. 16-01-2018
7 Workshop on techniques and processesses in biological and therapeutic research. 19-07-2018
8 Erudite invited lecture sponsored Kerala  Higher Education Council. Prof. Ajay Goel -‘Non-coding RNA biomarkers in gastrointestinal cancers: Where do we stand?' 18-02-2020
9 Tracking criminals using behavioral sciences: Application of digital forensics technologies 26-05-2020
10 Digitization of evidences from the crime scene 27-05-2020
11 Recent advancements in digital forensics 28-05-2020
12 Automation of digital evidence processing 29-05-2020
13 Application of revolutionary biochip array technology in Forensic Toxicology 30-05-2020
14 HPTLC and Forensic Applications 30-05-2020
15 Crime Prevention Through Environmental Design 05-06-2020
16 The Rise of Evidence-Based Policing 08-06-2020
17 The use of non-invasive, contactless digital autopsy in post mortem examination of COVID-19 death, the United Kingdom coronial service experience 11-06-2020
18 Forensics the missing link in the combat against wildlife crime 15-06-2020
19 Social media addiction and mental health 18-06-2020
20 Applied Criminology 24-06-2020
21 Evidence Multistat- A fully automated analyser to detect New Psychoactive substances and Roadside drug testing 27-06-2020
22 Enhancing and Analyzing Video Evidence 28-06-2020
23 End to end Automated DNA Forensic solutions and Databasing 04-07-2020
24 Detection of deception through modern forensic psychological investigation techniques’ 05-07-2020
25 Procedural Justice and Legitimacy in Policing 06-07-2020
26 Blockchain in Case Management 11-07-2020
27 Firearms Examination and Identification- An overview 11-07-2020
28 Maximize your forensic lab efficiency with advances to capillary electrophoresis (CE) workflow 17-07-2020
29 Psychological Autopsy 18-07-2020
30 Community Policing 21-07-2020
31 Rapid DNA technology for time-sensitive investigations 11-09-2020
32 Current status of Covid-19 Research and Epidemiology” by Rajiv Gandhi Institute of Developmental Studies (RGIDS) 19-11-2020
33 Crime scene investigation and evidence recognition: Practical experience 30-11-2020
34 Criminology- Transforming Theory into Practice 30-12-2020
  • M.Sc Labs (204,213,314,315,316,414,415)

  • Cell Culture Facility (111)

  • Computer Lab (103)

  • Instruments Room 1-3 (107-109)

  • Research Lab 1: Cell and Molecular Biology (410)

  • Research Lab 2: Neutraceuticals and Bioactives (110)

  • Research Lab 3: Pigment Research (211)

  • Research Lab 4: Photobiology and Phytochemicals (212)

  • Research Lab 5: Microbiology (303)

  • Research Lab 6: Bioprocess and Microbial Technology (313)

  • Research Lab 7: Behavioral Physiology (413)

  • Research Lab 8: Microbiology (416)

  1. Ph.Ds Awarded

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